Add to ORKGSummary: Recently developed methods that couple next-generation sequencing with chromosome conformation capture-based techniques, such as Hi-C and ChIA-PET, allow for characterization of genome-wide chromatin 3D structure. Understanding the organization of chromatin in three dimensions is a crucial next step in the unraveling of global gene regulation, and methods for analyzing such data are needed. We have developed HiBrowse, a user-friendly web-tool consisting of a range of hypothesis-based and descriptive statistics, using realistic assumptions in null-models. Availability and implementation: HiBrowse is supported by all major browsers, and is freely available a
My research will focus on the development of statistical and computational framework that jointly mo...
How DNA is organized in three dimensions inside the cell nucleus and how this affects the ways in wh...
Understanding how chromosomes fold provides insights into the transcription regulation, hence, the f...
Recently developed methods that couple next-generation sequencing with chromosome conformation captu...
DNA inside the nuclei of cells is folded into an intricate three-dimensional (3D) structure that inf...
Genome-wide 3C technologies (Hi-C) are being increasingly employed to study three-dimensional (3D) g...
Recent sequence-based profiling technologies such as high-throughput sequencing to detect fragment n...
Recent sequence-based profiling technologies such as high-throughput sequencing to detect fragment n...
The three-dimensional structure of the genome plays a key role in gene regulation. For example, whil...
The High-throughput Chromosome Conformation Capture (Hi-C) technique combines the power of the Next ...
The High-throughput Chromosome Conformation Capture (Hi-C) technique combines the power of the Next ...
The High-throughput Chromosome Conformation Capture (Hi-C) technique combines the power of the Next ...
The genome-wide investigation of chromatin organization enables insights into global gene expression...
My research will focus on the development of statistical and computational framework that jointly mo...
The hierarchical organization of chromatin is known to associate with diverse cellular functions; ho...
My research will focus on the development of statistical and computational framework that jointly mo...
How DNA is organized in three dimensions inside the cell nucleus and how this affects the ways in wh...
Understanding how chromosomes fold provides insights into the transcription regulation, hence, the f...
Recently developed methods that couple next-generation sequencing with chromosome conformation captu...
DNA inside the nuclei of cells is folded into an intricate three-dimensional (3D) structure that inf...
Genome-wide 3C technologies (Hi-C) are being increasingly employed to study three-dimensional (3D) g...
Recent sequence-based profiling technologies such as high-throughput sequencing to detect fragment n...
Recent sequence-based profiling technologies such as high-throughput sequencing to detect fragment n...
The three-dimensional structure of the genome plays a key role in gene regulation. For example, whil...
The High-throughput Chromosome Conformation Capture (Hi-C) technique combines the power of the Next ...
The High-throughput Chromosome Conformation Capture (Hi-C) technique combines the power of the Next ...
The High-throughput Chromosome Conformation Capture (Hi-C) technique combines the power of the Next ...
The genome-wide investigation of chromatin organization enables insights into global gene expression...
My research will focus on the development of statistical and computational framework that jointly mo...
The hierarchical organization of chromatin is known to associate with diverse cellular functions; ho...
My research will focus on the development of statistical and computational framework that jointly mo...
How DNA is organized in three dimensions inside the cell nucleus and how this affects the ways in wh...
Understanding how chromosomes fold provides insights into the transcription regulation, hence, the f...